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Topological estimation of signal flow in complex signaling networks
In a cell, any information about extra- or intra-cellular changes is transferred and processed through a signaling network and dysregulation of signal flow often leads to disease such as cancer. So, understanding of signal flow in the signaling network is critical to identify drug targets. Owing to...
Autores principales: | Lee, Daewon, Cho, Kwang-Hyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869720/ https://www.ncbi.nlm.nih.gov/pubmed/29588498 http://dx.doi.org/10.1038/s41598-018-23643-5 |
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