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Respiromics – An integrative analysis linking mitochondrial bioenergetics to molecular signatures

OBJECTIVE: Energy metabolism is challenged upon nutrient stress, eventually leading to a variety of metabolic diseases that represent a major global health burden. METHODS: Here, we combine quantitative mitochondrial respirometry (Seahorse technology) and proteomics (LC-MS/MS-based total protein app...

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Detalles Bibliográficos
Autores principales: Walheim, Ellen, Wiśniewski, Jacek R., Jastroch, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869730/
https://www.ncbi.nlm.nih.gov/pubmed/29361498
http://dx.doi.org/10.1016/j.molmet.2018.01.002