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MEF2A regulates mGluR-dependent AMPA receptor trafficking independently of Arc/Arg3.1

Differential trafficking of AMPA receptors (AMPARs) to and from the postsynaptic membrane is a key determinant of the strength of excitatory neurotransmission, and is thought to underlie learning and memory. The transcription factor MEF2 is a negative regulator of memory in vivo, in part by regulati...

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Detalles Bibliográficos
Autores principales: Carmichael, Ruth E., Wilkinson, Kevin A., Craig, Tim J., Ashby, Michael C., Henley, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869744/
https://www.ncbi.nlm.nih.gov/pubmed/29588465
http://dx.doi.org/10.1038/s41598-018-23440-0