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Excessive nerve growth factor impairs bidirectional communication between the oocyte and cumulus cells resulting in reduced oocyte competence

BACKGROUND: Excessive nerve growth factor (NGF) is commonly found in the follicular fluid of patients with polycystic ovary syndrome (PCOS). Furthermore, oocytes from PCOS patients exhibit lower developmental competence. The purpose of this study was to explore the association between excessive NGF...

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Detalles Bibliográficos
Autores principales: Zhai, Yiwen, Yao, Guidong, Rao, Faiza, Wang, Yong, Song, Xiaoyuan, Sun, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869770/
https://www.ncbi.nlm.nih.gov/pubmed/29580253
http://dx.doi.org/10.1186/s12958-018-0349-7