An Autoimmune Disease-Associated Risk Variant in the TNFAIP3 Gene Plays a Protective Role in Brucellosis That Is Mediated by the NF-κB Signaling Pathway

Naturally occurring functional variants (rs148314165 and rs200820567, collectively referred to as TT>A) reduce the expression of the tumor necrosis factor alpha-induced protein 3 (TNFAIP3) gene, a negative regulator of NF-κB signaling, and predispose individuals to autoimmune disease. In this ana...

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Detalles Bibliográficos
Autores principales: Lou, Lixin, Bao, Wanguo, Liu, Xianjun, Song, Hongxiao, Wang, Yang, Zhang, Kaiyu, Gao, Wenjing, Li, Haijun, Tu, Zhengkun, Wang, Shaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Bacteriology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869838/
https://www.ncbi.nlm.nih.gov/pubmed/29343543
http://dx.doi.org/10.1128/JCM.01363-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869838/
https://www.ncbi.nlm.nih.gov/pubmed/29343543
http://dx.doi.org/10.1128/JCM.01363-17

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