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The mammalian ULK1 complex and autophagy initiation

Autophagy is a vital lysosomal degradation pathway that serves as a quality control mechanism. It rids the cell of damaged, toxic or excess cellular components, which if left to persist could be detrimental to the cell. It also serves as a recycling pathway to maintain protein synthesis under starva...

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Detalles Bibliográficos
Autores principales: Zachari, Maria, Ganley, Ian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869855/
https://www.ncbi.nlm.nih.gov/pubmed/29233870
http://dx.doi.org/10.1042/EBC20170021