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Dysregulation of autophagy as a common mechanism in lysosomal storage diseases

The lysosome plays a pivotal role between catabolic and anabolic processes as the nexus for signalling pathways responsive to a variety of factors, such as growth, nutrient availability, energetic status and cellular stressors. Lysosomes are also the terminal degradative organelles for autophagy thr...

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Detalles Bibliográficos
Autores principales: Seranova, Elena, Connolly, Kyle J., Zatyka, Malgorzata, Rosenstock, Tatiana R., Barrett, Timothy, Tuxworth, Richard I., Sarkar, Sovan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869865/
https://www.ncbi.nlm.nih.gov/pubmed/29233882
http://dx.doi.org/10.1042/EBC20170055