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Adverse outcome pathways: Application to enhance mechanistic understanding of neurotoxicity
Recent developments have prompted the transition of empirically based testing of late stage toxicity in animals for a range of different endpoints including neurotoxicity to more efficient and predictive mechanistically based approaches with greater emphasis on measurable key events early in the pro...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Pergamon Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869951/ https://www.ncbi.nlm.nih.gov/pubmed/28529068 http://dx.doi.org/10.1016/j.pharmthera.2017.05.006 |