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Oxidative Stress, Amyloid-β Peptide, and Altered Key Molecular Pathways in the Pathogenesis and Progression of Alzheimer’s Disease

Oxidative stress is implicated in the pathogenesis and progression of Alzheimer’s disease (AD) and its earlier stage, amnestic mild cognitive impairment (aMCI). One source of oxidative stress in AD and aMCI brains is that associated with amyloid-β peptide, Aβ(1-42) oligomers. Our laboratory first sh...

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Detalles Bibliográficos
Autores principales: Butterfield, D. Allan, Boyd-Kimball, Debra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870019/
https://www.ncbi.nlm.nih.gov/pubmed/29562527
http://dx.doi.org/10.3233/JAD-170543