TRPC1 Deletion Causes Striatal Neuronal Cell Apoptosis and Proteomic Alterations in Mice

Transient receptor potential channel 1 (TRPC1) is widely expressed throughout the nervous system, while its biological role remains unclear. In this study, we showed that TRPC1 deletion caused striatal neuronal loss and significantly increased TUNEL-positive and 8-hydroxy-2′-deoxyguanosine (8-OHdG)...

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Detalles Bibliográficos
Autores principales: Wang, Dian, Yu, Haitao, Xu, Benhong, Xu, Hua, Zhang, Zaijun, Ren, Xiaohu, Yuan, Jianhui, Liu, Jianjun, Guo, Yi, Spencer, Peter S., Yang, Xifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870053/
https://www.ncbi.nlm.nih.gov/pubmed/29615894
http://dx.doi.org/10.3389/fnagi.2018.00072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870053/
https://www.ncbi.nlm.nih.gov/pubmed/29615894
http://dx.doi.org/10.3389/fnagi.2018.00072

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