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TRPC1 Deletion Causes Striatal Neuronal Cell Apoptosis and Proteomic Alterations in Mice
Transient receptor potential channel 1 (TRPC1) is widely expressed throughout the nervous system, while its biological role remains unclear. In this study, we showed that TRPC1 deletion caused striatal neuronal loss and significantly increased TUNEL-positive and 8-hydroxy-2′-deoxyguanosine (8-OHdG)...
Autores principales: | Wang, Dian, Yu, Haitao, Xu, Benhong, Xu, Hua, Zhang, Zaijun, Ren, Xiaohu, Yuan, Jianhui, Liu, Jianjun, Guo, Yi, Spencer, Peter S., Yang, Xifei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870053/ https://www.ncbi.nlm.nih.gov/pubmed/29615894 http://dx.doi.org/10.3389/fnagi.2018.00072 |
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