Genome-Wide Analyses Identify Filamin-A As a Novel Downstream Target for Insulin and IGF1 Action

Insulin analogs were developed to improve diabetes therapy. However, certain modifications introduced into the insulin molecule were shown to enhance their affinity to the insulin-like growth factor-1 receptor (IGF1R). Most tumors, including endometrial cancers, express high levels of IGF1R. The pre...

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Detalles Bibliográficos
Autores principales: Aizen, Daniel, Pasmanik-Chor, Metsada, Sarfstein, Rive, Laron, Zvi, Bruchim, Ilan, Werner, Haim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870203/
https://www.ncbi.nlm.nih.gov/pubmed/29615978
http://dx.doi.org/10.3389/fendo.2018.00105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870203/
https://www.ncbi.nlm.nih.gov/pubmed/29615978
http://dx.doi.org/10.3389/fendo.2018.00105

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