Synergistic anti-proliferative effects of combination of ABT-263 and MCL-1 selective inhibitor A-1210477 on cervical cancer cell lines

OBJECTIVE: There are number of studies which report that BCL-2 anti-apoptotic proteins (e.g. BCL-2, BCL-XL, and MCL-1) are highly expressed in cervical cancer tissues compared to the normal cervical epithelia. Despite these reports, targeting these proteins for cervical cancer treatment has not been...

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Detalles Bibliográficos
Autores principales: Lian, Benedict Shi Xiang, Yek, Angeline En Hui, Shuvas, Hemalata, Abdul Rahman, Siti Fairus, Muniandy, Kalaivani, Mohana-Kumaran, Nethia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870236/
https://www.ncbi.nlm.nih.gov/pubmed/29580266
http://dx.doi.org/10.1186/s13104-018-3302-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870236/
https://www.ncbi.nlm.nih.gov/pubmed/29580266
http://dx.doi.org/10.1186/s13104-018-3302-0

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