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Enhanced expression of histone chaperone APLF associate with breast cancer

DNA damage-specific histone chaperone Aprataxin PNK-like factor (APLF) regulates mesenchymal-to-epithelial transition (MET) during cellular reprogramming. We investigated the role of APLF in epithelial-to-mesenchymal transition (EMT) linked to breast cancer invasiveness and metastasis. Here, we show...

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Detalles Bibliográficos
Autores principales: Majumder, Aditi, Syed, Khaja Moheiddin, Mukherjee, Ananda, Lankadasari, Manendra Babu, Azeez, Juberiya Mohammed, Sreeja, Sreeharshan, Harikumar, Kuzhuvelil B., Pillai, Madhavan Radhakrishna, Dutta, Debasree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870250/
https://www.ncbi.nlm.nih.gov/pubmed/29580241
http://dx.doi.org/10.1186/s12943-018-0826-9