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Elucidating the Metabolic Plasticity of Cancer: Mitochondrial Reprogramming and Hybrid Metabolic States

Aerobic glycolysis, also referred to as the Warburg effect, has been regarded as the dominant metabolic phenotype in cancer cells for a long time. More recently, it has been shown that mitochondria in most tumors are not defective in their ability to carry out oxidative phosphorylation (OXPHOS). Ins...

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Detalles Bibliográficos
Autores principales: Jia, Dongya, Park, Jun Hyoung, Jung, Kwang Hwa, Levine, Herbert, Kaipparettu, Benny Abraham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870353/
https://www.ncbi.nlm.nih.gov/pubmed/29534029
http://dx.doi.org/10.3390/cells7030021