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Beta-globin gene haplotypes and selected Malaria-associated variants among black Southern African populations

Partial carrier-resistance to Plasmodium falciparum malaria conferred by the sickle cell (HbS) mutation has resulted in the local amplification and positive selection of sickle cell disease (SCD) in malaria-endemic regions and particularly in sub-Saharan Africa (SSA). The present study investigated...

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Detalles Bibliográficos
Autores principales: Pule, G. D., Chimusa, E. R., Mnika, K., Mhandire, K., Kampira, E., Dandara, C., Wonkam, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870409/
https://www.ncbi.nlm.nih.gov/pubmed/29868223
http://dx.doi.org/10.1017/gheg.2017.14