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Transcriptional Responses Reveal Similarities Between Preclinical Rat Liver Testing Systems

Toxicogenomics (TGx) is an important tool to gain an enhanced understanding of toxicity at the molecular level. Previously, we developed a pair ranking (PRank) method to assess in vitro to in vivo extrapolation (IVIVE) using toxicogenomic datasets from the Open Toxicogenomics Project-Genomics Assist...

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Detalles Bibliográficos
Autores principales: Liu, Zhichao, Delavan, Brian, Roberts, Ruth, Tong, Weida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870427/
https://www.ncbi.nlm.nih.gov/pubmed/29616076
http://dx.doi.org/10.3389/fgene.2018.00074