High circulating angiopoietin-2 levels exacerbate pulmonary inflammation but not vascular leak or mortality in endotoxin-induced lung injury in mice

BACKGROUND: Elevated plasma levels of angiopoietin-2 (ANGPT2) have been reported in patients with acute lung injury (ALI); however, it remains unclear whether this increase contributes to, or just marks, the underlying vasculopathic inflammation and leak associated with ALI. Here we investigated the...

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Detalles Bibliográficos
Autores principales: Schlosser, Kenny, Taha, Mohamad, Deng, Yupu, McIntyre, Lauralyn A, Mei, Shirley H J, Stewart, Duncan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Pulmonary Vasculature
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870448/
https://www.ncbi.nlm.nih.gov/pubmed/28947667
http://dx.doi.org/10.1136/thoraxjnl-2017-210413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870448/
https://www.ncbi.nlm.nih.gov/pubmed/28947667
http://dx.doi.org/10.1136/thoraxjnl-2017-210413

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