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Association testing of bisulfite-sequencing methylation data via a Laplace approximation
MOTIVATION: Epigenome-wide association studies can provide novel insights into the regulation of genes involved in traits and diseases. The rapid emergence of bisulfite-sequencing technologies enables performing such genome-wide studies at the resolution of single nucleotides. However, analysis of d...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870555/ https://www.ncbi.nlm.nih.gov/pubmed/28881982 http://dx.doi.org/10.1093/bioinformatics/btx248 |