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Association testing of bisulfite-sequencing methylation data via a Laplace approximation

MOTIVATION: Epigenome-wide association studies can provide novel insights into the regulation of genes involved in traits and diseases. The rapid emergence of bisulfite-sequencing technologies enables performing such genome-wide studies at the resolution of single nucleotides. However, analysis of d...

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Detalles Bibliográficos
Autores principales: Weissbrod, Omer, Rahmani, Elior, Schweiger, Regev, Rosset, Saharon, Halperin, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870555/
https://www.ncbi.nlm.nih.gov/pubmed/28881982
http://dx.doi.org/10.1093/bioinformatics/btx248