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Direct AUC optimization of regulatory motifs

MOTIVATION: The discovery of transcription factor binding site (TFBS) motifs is essential for untangling the complex mechanism of genetic variation under different developmental and environmental conditions. Among the huge amount of computational approaches for de novo identification of TFBS motifs,...

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Detalles Bibliográficos
Autores principales: Zhu, Lin, Zhang, Hong-Bo, Huang, De-Shuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870558/
https://www.ncbi.nlm.nih.gov/pubmed/28881989
http://dx.doi.org/10.1093/bioinformatics/btx255