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Direct AUC optimization of regulatory motifs
MOTIVATION: The discovery of transcription factor binding site (TFBS) motifs is essential for untangling the complex mechanism of genetic variation under different developmental and environmental conditions. Among the huge amount of computational approaches for de novo identification of TFBS motifs,...
Autores principales: | Zhu, Lin, Zhang, Hong-Bo, Huang, De-Shuang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870558/ https://www.ncbi.nlm.nih.gov/pubmed/28881989 http://dx.doi.org/10.1093/bioinformatics/btx255 |
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