CACUL1 reciprocally regulates SIRT1 and LSD1 to repress PPARγ and inhibit adipogenesis

Peroxisome proliferator-activated receptor γ (PPARγ) is the master regulator of adipocyte differentiation and is closely linked to the development of obesity. Despite great progress in elucidating the transcriptional network of PPARγ, epigenetic regulation of this pathway by histone modification rem...

Descripción completa

Detalles Bibliográficos
Autores principales: Jang, Min Jun, Park, Ui-Hyun, Kim, Jeong Woo, Choi, Hanbyeul, Um, Soo-Jong, Kim, Eun-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870580/
https://www.ncbi.nlm.nih.gov/pubmed/29233982
http://dx.doi.org/10.1038/s41419-017-0070-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870580/
https://www.ncbi.nlm.nih.gov/pubmed/29233982
http://dx.doi.org/10.1038/s41419-017-0070-z

Ejemplares similares