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CACUL1 reciprocally regulates SIRT1 and LSD1 to repress PPARγ and inhibit adipogenesis
Peroxisome proliferator-activated receptor γ (PPARγ) is the master regulator of adipocyte differentiation and is closely linked to the development of obesity. Despite great progress in elucidating the transcriptional network of PPARγ, epigenetic regulation of this pathway by histone modification rem...
Autores principales: | Jang, Min Jun, Park, Ui-Hyun, Kim, Jeong Woo, Choi, Hanbyeul, Um, Soo-Jong, Kim, Eun-Joo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870580/ https://www.ncbi.nlm.nih.gov/pubmed/29233982 http://dx.doi.org/10.1038/s41419-017-0070-z |
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