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circHIPK2-mediated σ-1R promotes endoplasmic reticulum stress in human pulmonary fibroblasts exposed to silica

Silicosis is characterized by fibroblast accumulation and excessive deposition of extracellular matrix. Although the roles of SiO(2)-induced chemokines and cytokines released from alveolar macrophages have received significant attention, the direct effects of SiO(2) on protein production and functio...

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Detalles Bibliográficos
Autores principales: Cao, Zhouli, Xiao, Qingling, Dai, Xiaoniu, Zhou, Zewei, Jiang, Rong, Cheng, Yusi, Yang, Xiyue, Guo, Huifang, Wang, Jing, Xi, Zhaoqing, Yao, Honghong, Chao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870587/
https://www.ncbi.nlm.nih.gov/pubmed/29238093
http://dx.doi.org/10.1038/s41419-017-0017-4