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Long non-coding RNA MEG3 functions as a competing endogenous RNA to regulate ischemic neuronal death by targeting miR-21/PDCD4 signaling pathway

Long non-coding RNA (lncRNA) maternally expressed gene 3 (MEG3) has been demonstrated as an important regulator in diverse human cancers. However, its function and regulatory mechanism in ischemic stroke remains largely unknown. Here, we report that MEG3 is physically associated with microRNA-21 (mi...

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Detalles Bibliográficos
Autores principales: Yan, Honglin, Rao, Jie, Yuan, Jingping, Gao, Likun, Huang, Wenxian, Zhao, Lina, Ren, Jiacai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870589/
https://www.ncbi.nlm.nih.gov/pubmed/29238035
http://dx.doi.org/10.1038/s41419-017-0047-y