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BCL-X(L) overexpression promotes tumor progression-associated properties

By using human melanoma and glioblastoma cell lines and their derivative BCL-X(L) overexpressing clones, we investigated the role of BCL-X(L) in aggressive features of these two tumor histotypes. We found that in both models, BCL-X(L) overexpression increased in vitro cell migration and invasion and...

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Detalles Bibliográficos
Autores principales: Trisciuoglio, Daniela, Tupone, Maria Grazia, Desideri, Marianna, Di Martile, Marta, Gabellini, Chiara, Buglioni, Simonetta, Pallocca, Matteo, Alessandrini, Gabriele, D’Aguanno, Simona, Del Bufalo, Donatella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870591/
https://www.ncbi.nlm.nih.gov/pubmed/29238043
http://dx.doi.org/10.1038/s41419-017-0055-y