Implication of 4E-BP1 protein dephosphorylation and accumulation in pancreatic cancer cell death induced by combined gemcitabine and TRAIL

Pancreatic cancer cells show varying sensitivity to the anticancer effects of gemcitabine. However, as a chemotherapeutic agent, gemcitabine can cause intolerably high levels of toxicity and patients often develop resistance to the beneficial effects of this drug. Combination studies show that use o...

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Detalles Bibliográficos
Autores principales: Elia, Androulla, Henry-Grant, Ricky, Adiseshiah, Charlotte, Marboeuf, Catherine, Buckley, Rebecca J, Clemens, Michael J, Mudan, Satvinder, Pyronnet, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870593/
https://www.ncbi.nlm.nih.gov/pubmed/29233971
http://dx.doi.org/10.1038/s41419-017-0001-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870593/
https://www.ncbi.nlm.nih.gov/pubmed/29233971
http://dx.doi.org/10.1038/s41419-017-0001-z

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