Implication of 4E-BP1 protein dephosphorylation and accumulation in pancreatic cancer cell death induced by combined gemcitabine and TRAIL

Pancreatic cancer cells show varying sensitivity to the anticancer effects of gemcitabine. However, as a chemotherapeutic agent, gemcitabine can cause intolerably high levels of toxicity and patients often develop resistance to the beneficial effects of this drug. Combination studies show that use o...

Descripción completa

Detalles Bibliográficos
Autores principales: Elia, Androulla, Henry-Grant, Ricky, Adiseshiah, Charlotte, Marboeuf, Catherine, Buckley, Rebecca J, Clemens, Michael J, Mudan, Satvinder, Pyronnet, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870593/
https://www.ncbi.nlm.nih.gov/pubmed/29233971
http://dx.doi.org/10.1038/s41419-017-0001-z

Ejemplares similares

Ejemplares similares