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Helicobacter pylori VacA induces autophagic cell death in gastric epithelial cells via the endoplasmic reticulum stress pathway

The Helicobacter pylori vacuolating cytotoxin (VacA) can promote progressive vacuolation and gastric injury and may be associated with human gastric cancer. Increasing evidence indicates that autophagy is involved in the cell death induced by VacA, but the specific mechanisms need to be further eluc...

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Detalles Bibliográficos
Autores principales: Zhu, Pan, Xue, Jun, Zhang, Zhu-jun, Jia, Yin-ping, Tong, Ya-nan, Han, Dan, Li, Qian, Xiang, Yang, Mao, Xu-hu, Tang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870595/
https://www.ncbi.nlm.nih.gov/pubmed/29238039
http://dx.doi.org/10.1038/s41419-017-0011-x