HRD1 prevents apoptosis in renal tubular epithelial cells by mediating eIF2α ubiquitylation and degradation

Apoptosis of renal tubular epithelial cells is a key feature of the pathogenicity associated with tubulointerstitial fibrosis and other kidney diseases. One factor that regulates important cellular processes like apoptosis and cell proliferation is HRD1, an E3 ubiquitin ligase that acts by promoting...

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Detalles Bibliográficos
Autores principales: Huang, Yujie, Sun, Yifei, Cao, Yizhi, Sun, Hui, Li, Min, You, Hui, Su, Dongming, Li, Yanjiao, Liang, Xiubin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870601/
https://www.ncbi.nlm.nih.gov/pubmed/29233968
http://dx.doi.org/10.1038/s41419-017-0002-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870601/
https://www.ncbi.nlm.nih.gov/pubmed/29233968
http://dx.doi.org/10.1038/s41419-017-0002-y

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