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pgRNAFinder: a web-based tool to design distance independent paired-gRNA

SUMMARY: The CRISPR/Cas System has been shown to be an efficient and accurate genome-editing technique. There exist a number of tools to design the guide RNA sequences and predict potential off-target sites. However, most of the existing computational tools on gRNA design are restricted to small del...

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Detalles Bibliográficos
Autores principales: Xiong, Yuanyan, Xie, Xiaowei, Wang, Yanzhi, Ma, Wenbing, Liang, Puping, Songyang, Zhou, Dai, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870604/
https://www.ncbi.nlm.nih.gov/pubmed/28961776
http://dx.doi.org/10.1093/bioinformatics/btx472