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pgRNAFinder: a web-based tool to design distance independent paired-gRNA
SUMMARY: The CRISPR/Cas System has been shown to be an efficient and accurate genome-editing technique. There exist a number of tools to design the guide RNA sequences and predict potential off-target sites. However, most of the existing computational tools on gRNA design are restricted to small del...
Autores principales: | Xiong, Yuanyan, Xie, Xiaowei, Wang, Yanzhi, Ma, Wenbing, Liang, Puping, Songyang, Zhou, Dai, Zhiming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870604/ https://www.ncbi.nlm.nih.gov/pubmed/28961776 http://dx.doi.org/10.1093/bioinformatics/btx472 |
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