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Benchmarking substrate-based kinase activity inference using phosphoproteomic data
MOTIVATION: Phosphoproteomic experiments are increasingly used to study the changes in signaling occurring across different conditions. It has been proposed that changes in phosphorylation of kinase target sites can be used to infer when a kinase activity is under regulation. However, these approach...
Autores principales: | Hernandez-Armenta, Claudia, Ochoa, David, Gonçalves, Emanuel, Saez-Rodriguez, Julio, Beltrao, Pedro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870625/ https://www.ncbi.nlm.nih.gov/pubmed/28200105 http://dx.doi.org/10.1093/bioinformatics/btx082 |
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