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Benchmarking substrate-based kinase activity inference using phosphoproteomic data

MOTIVATION: Phosphoproteomic experiments are increasingly used to study the changes in signaling occurring across different conditions. It has been proposed that changes in phosphorylation of kinase target sites can be used to infer when a kinase activity is under regulation. However, these approach...

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Detalles Bibliográficos
Autores principales: Hernandez-Armenta, Claudia, Ochoa, David, Gonçalves, Emanuel, Saez-Rodriguez, Julio, Beltrao, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870625/
https://www.ncbi.nlm.nih.gov/pubmed/28200105
http://dx.doi.org/10.1093/bioinformatics/btx082