Elucidating essential kinases of endothelin signalling by logic modelling of phosphoproteomics data

Endothelins (EDN) are peptide hormones that activate a GPCR signalling system and contribute to several diseases, including hypertension and cancer. Current knowledge about EDN signalling is fragmentary, and no systems level understanding is available. We investigated phosphoproteomic changes caused...

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Detalles Bibliográficos
Autores principales: Schäfer, Alexander, Gjerga, Enio, Welford, Richard WD, Renz, Imke, Lehembre, Francois, Groenen, Peter MA, Saez‐Rodriguez, Julio, Aebersold, Ruedi, Gstaiger, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683863/
https://www.ncbi.nlm.nih.gov/pubmed/31464372
http://dx.doi.org/10.15252/msb.20198828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683863/
https://www.ncbi.nlm.nih.gov/pubmed/31464372
http://dx.doi.org/10.15252/msb.20198828

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