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Reconstructing phosphorylation signalling networks from quantitative phosphoproteomic data

Cascades of phosphorylation between protein kinases comprise a core mechanism in the integration and propagation of intracellular signals. Although we have accumulated a wealth of knowledge around some such pathways, this is subject to study biases and much remains to be uncovered. Phosphoproteomics...

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Detalles Bibliográficos
Autores principales: Invergo, Brandon M., Beltrao, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204553/
https://www.ncbi.nlm.nih.gov/pubmed/30072490
http://dx.doi.org/10.1042/EBC20180019