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A scalable moment-closure approximation for large-scale biochemical reaction networks

MOTIVATION: Stochastic molecular processes are a leading cause of cell-to-cell variability. Their dynamics are often described by continuous-time discrete-state Markov chains and simulated using stochastic simulation algorithms. As these stochastic simulations are computationally demanding, ordinary...

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Detalles Bibliográficos
Autores principales: Kazeroonian, Atefeh, Theis, Fabian J, Hasenauer, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870627/
https://www.ncbi.nlm.nih.gov/pubmed/28881983
http://dx.doi.org/10.1093/bioinformatics/btx249