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popFBA: tackling intratumour heterogeneity with Flux Balance Analysis
MOTIVATION: Intratumour heterogeneity poses many challenges to the treatment of cancer. Unfortunately, the transcriptional and metabolic information retrieved by currently available computational and experimental techniques portrays the average behaviour of intermixed and heterogeneous cell subpopul...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870635/ https://www.ncbi.nlm.nih.gov/pubmed/28881985 http://dx.doi.org/10.1093/bioinformatics/btx251 |