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popFBA: tackling intratumour heterogeneity with Flux Balance Analysis

MOTIVATION: Intratumour heterogeneity poses many challenges to the treatment of cancer. Unfortunately, the transcriptional and metabolic information retrieved by currently available computational and experimental techniques portrays the average behaviour of intermixed and heterogeneous cell subpopul...

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Detalles Bibliográficos
Autores principales: Damiani, Chiara, Di Filippo, Marzia, Pescini, Dario, Maspero, Davide, Colombo, Riccardo, Mauri, Giancarlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870635/
https://www.ncbi.nlm.nih.gov/pubmed/28881985
http://dx.doi.org/10.1093/bioinformatics/btx251