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popFBA: tackling intratumour heterogeneity with Flux Balance Analysis

MOTIVATION: Intratumour heterogeneity poses many challenges to the treatment of cancer. Unfortunately, the transcriptional and metabolic information retrieved by currently available computational and experimental techniques portrays the average behaviour of intermixed and heterogeneous cell subpopul...

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Detalles Bibliográficos
Autores principales:	Damiani, Chiara, Di Filippo, Marzia, Pescini, Dario, Maspero, Davide, Colombo, Riccardo, Mauri, Giancarlo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Ismb/Eccb 2017: The 25th Annual Conference Intelligent Systems for Molecular Biology Held Jointly with the 16th Annual European Conference on Computational Biology, Prague, Czech Republic, July 21–25, 2017
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870635/ https://www.ncbi.nlm.nih.gov/pubmed/28881985 http://dx.doi.org/10.1093/bioinformatics/btx251

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