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DeepBound: accurate identification of transcript boundaries via deep convolutional neural fields

MOTIVATION: Reconstructing the full-length expressed transcripts (a.k.a. the transcript assembly problem) from the short sequencing reads produced by RNA-seq protocol plays a central role in identifying novel genes and transcripts as well as in studying gene expressions and gene functions. A crucial...

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Detalles Bibliográficos
Autores principales: Shao, Mingfu, Ma, Jianzhu, Wang, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870651/
https://www.ncbi.nlm.nih.gov/pubmed/28881999
http://dx.doi.org/10.1093/bioinformatics/btx267