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Sequence2Vec: a novel embedding approach for modeling transcription factor binding affinity landscape

MOTIVATION: An accurate characterization of transcription factor (TF)-DNA affinity landscape is crucial to a quantitative understanding of the molecular mechanisms underpinning endogenous gene regulation. While recent advances in biotechnology have brought the opportunity for building binding affini...

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Detalles Bibliográficos
Autores principales: Dai, Hanjun, Umarov, Ramzan, Kuwahara, Hiroyuki, Li, Yu, Song, Le, Gao, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870668/
https://www.ncbi.nlm.nih.gov/pubmed/28961686
http://dx.doi.org/10.1093/bioinformatics/btx480