Degenerate codon mixing for PCR-based manipulation of highly repetitive sequences

OBJECTIVE: Repeat expansion of polyglutamine tracks leads to a group of inherited human neurodegenerative disorders. Studying such repetitive sequences is required to gain insight into the pathophysiology of these diseases. PCR-based manipulation of repetitive sequences, however, is challenging due...

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Detalles Bibliográficos
Autores principales: Ratnayake, Dhanushika, Newman, Morgan, Lardelli, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870680/
https://www.ncbi.nlm.nih.gov/pubmed/29587822
http://dx.doi.org/10.1186/s13104-018-3298-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870680/
https://www.ncbi.nlm.nih.gov/pubmed/29587822
http://dx.doi.org/10.1186/s13104-018-3298-5

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