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Degenerate codon mixing for PCR-based manipulation of highly repetitive sequences
OBJECTIVE: Repeat expansion of polyglutamine tracks leads to a group of inherited human neurodegenerative disorders. Studying such repetitive sequences is required to gain insight into the pathophysiology of these diseases. PCR-based manipulation of repetitive sequences, however, is challenging due...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870680/ https://www.ncbi.nlm.nih.gov/pubmed/29587822 http://dx.doi.org/10.1186/s13104-018-3298-5 |