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Genotype-specific and cross-reactive neutralizing antibodies induced by dengue virus infection: detection of antibodies with different levels of neutralizing activities against homologous and heterologous genotypes of dengue virus type 2 in common marmosets (Callithrix jacchus)

BACKGROUND: A vaccine against all four dengue virus (DENV) serotypes includes the formulation of one genotype of each serotype. Although genetic similarities among genotypes within a serotype are higher as compared to those among serotypes, differences in the immunogenicity of the included genotypes...

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Detalles Bibliográficos
Autores principales: Azami, Nor Azila Muhammad, Moi, Meng Ling, Ami, Yasushi, Suzaki, Yuriko, Lim, Chang-Kweng, Taniguchi, Satoshi, Saijo, Masayuki, Takasaki, Tomohiko, Kurane, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870686/
https://www.ncbi.nlm.nih.gov/pubmed/29587780
http://dx.doi.org/10.1186/s12985-018-0967-x