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Inhibition of HIV early replication by the p53 and its downstream gene p21

BACKGROUND: The tumor suppressor gene p53 has been found to suppress HIV infection by various mechanisms, but the inhibition of HIV at an early stage of replication by host cell p53 and its downstream gene p21 has not been well studied. METHOD: VSV-G pseudotyped HIV-1 or HIV-2 viruses with GFP or lu...

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Detalles Bibliográficos
Autores principales: Shi, Binshan, Sharifi, Hamayun J., DiGrigoli, Sara, Kinnetz, Michaela, Mellon, Katie, Hu, Wenwei, de Noronha, Carlos M. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870690/
https://www.ncbi.nlm.nih.gov/pubmed/29587790
http://dx.doi.org/10.1186/s12985-018-0959-x