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5′/ 3′ imbalance strategy to detect ALK fusion genes in circulating tumor RNA from patients with non-small cell lung cancer

BACKGROUND: Detecting an ALK fusion gene in patients with non-small cell lung cancer (NSCLC) could provide evidence to guide individualized therapy. METHODS: The 5′/3′ imbalance strategy for quantitative reverse transcription-PCR (RT-qPCR) was developed to detect ALK fusion genes in circulating tumo...

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Detalles Bibliográficos
Autores principales: Tong, Yongqing, Zhao, Zhijun, Liu, Bei, Bao, Anyu, Zheng, Hongyun, Gu, Jian, McGrath, Mary, Xia, Ying, Tan, Bihua, Song, Chunhua, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870746/
https://www.ncbi.nlm.nih.gov/pubmed/29587818
http://dx.doi.org/10.1186/s13046-018-0735-1