Cargando…

DEIsoM: a hierarchical Bayesian model for identifying differentially expressed isoforms using biological replicates

MOTIVATION: High-throughput mRNA sequencing (RNA-Seq) is a powerful tool for quantifying gene expression. Identification of transcript isoforms that are differentially expressed in different conditions, such as in patients and healthy subjects, can provide insights into the molecular basis of diseas...

Descripción completa

Detalles Bibliográficos
Autores principales: Peng, Hao, Yang, Yifan, Zhe, Shandian, Wang, Jian, Gribskov, Michael, Qi, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870796/
https://www.ncbi.nlm.nih.gov/pubmed/28595376
http://dx.doi.org/10.1093/bioinformatics/btx357