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DEIsoM: a hierarchical Bayesian model for identifying differentially expressed isoforms using biological replicates
MOTIVATION: High-throughput mRNA sequencing (RNA-Seq) is a powerful tool for quantifying gene expression. Identification of transcript isoforms that are differentially expressed in different conditions, such as in patients and healthy subjects, can provide insights into the molecular basis of diseas...
Autores principales: | Peng, Hao, Yang, Yifan, Zhe, Shandian, Wang, Jian, Gribskov, Michael, Qi, Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870796/ https://www.ncbi.nlm.nih.gov/pubmed/28595376 http://dx.doi.org/10.1093/bioinformatics/btx357 |
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