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Deconvolution of multiple infections in Plasmodium falciparum from high throughput sequencing data

MOTIVATION: The presence of multiple infecting strains of the malarial parasite Plasmodium falciparum affects key phenotypic traits, including drug resistance and risk of severe disease. Advances in protocols and sequencing technology have made it possible to obtain high-coverage genome-wide sequenc...

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Detalles Bibliográficos
Autores principales: Zhu, Sha Joe, Almagro-Garcia, Jacob, McVean, Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870807/
https://www.ncbi.nlm.nih.gov/pubmed/28961721
http://dx.doi.org/10.1093/bioinformatics/btx530