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Deconvolution of multiple infections in Plasmodium falciparum from high throughput sequencing data
MOTIVATION: The presence of multiple infecting strains of the malarial parasite Plasmodium falciparum affects key phenotypic traits, including drug resistance and risk of severe disease. Advances in protocols and sequencing technology have made it possible to obtain high-coverage genome-wide sequenc...
Autores principales: | Zhu, Sha Joe, Almagro-Garcia, Jacob, McVean, Gil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870807/ https://www.ncbi.nlm.nih.gov/pubmed/28961721 http://dx.doi.org/10.1093/bioinformatics/btx530 |
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